What to know
The University of Minnesota provided real-time next-generation sequencing and analysis of SARS-CoV-2 in Minnesota. Awarded in 2021, this project established the University of Minnesota Genomics Center (UMGC) as a regional SARS-CoV-2 sequencing hub and facilitated a low-cost and high-output genomic sequencing method. In addition, the project provided research on how the host and virus interact with one another during infection, as well as the potential for reinfection.
Findings on SARS-CoV-2 surveillance and investigations
Researchers created a cost-effective and highly scalable tailed amplicon method for SARS-CoV-2 sequencing.1 They then used this method to sequence >7,500 SARS-CoV-2 samples from across the Midwest. Researchers also made this protocol and the primer pools used to carry out the method available to laboratories in the SPHERES consortium.
- An online protocol for the tailed amplicon method is available: SARS-CoV-2 Tailed Amplicon Illumina Sequencing V.2
Content Source
Error processing SSI file
About This Page
Published: May 15, 2024
Updated: January 30, 2024
This page was last updated on this date. Updates may include minor edits, image changes, or other modifications to page content.
Reviewed: January 30, 2024
The information on this page was last reviewed by subject matter experts to ensure accuracy.
- A Rapid, Cost-Effective Tailed Amplicon Method for Sequencing SARS-CoV-2. BMC Genomics, 2020.