Gene-Environment-Time Interactions in Neurodegenerative Diseases: Hypotheses and Research Approaches
Affiliates | Walter G. Bradley [1], Angeline S. Andrew [2], Bryan J. Traynor [3,4], Adriano Chiò [5], Tanya H. Butt [2], & Elijah W. Stommel [2]
[1] Department of Neurology, Miller School of Medicine, University of Miami |
Journal | Annals of Neurosciences |
Summary | This paper proposes a hypothesis to explain the syndrome of ALS based on the interaction of many individual environmental risk factors with many individual genetic predisposing factors. It’s hypothesized that there are many such combinations of individual, specific, genetic, and environmental factors, and that each combination can lead to the development of the syndrome of ALS. |
Link to paper | Find the paper here! |