Next Generation Sequencing in Clinical Practice: Current Status and Future Needs

During the past 5 years, next-generation sequencing (NGS) has transitioned from research to clinical use. At least 14 countries have created initiatives to sequence large populations, and it is projected that more than 60 million people worldwide will have their genome sequenced by 2025. However, there has not been an assessment of global NGS implementation. Understanding how NGS is being used and paid for is critical for determining its clinical and economic benefits and addressing current and future challenges to appropriate implementation.
Dr Phillips will discuss the current state of implementation of next generation sequencing in clinical practice, challenges ahead, and the need for additional data on implementation and outcomes including economic data and linkages of clinical and public health data. Dr Philips is a leader in the application of new technologies to improve healthcare. She is the Founding Director of the UCSF Center for Translational and Policy Research on Personalized Medicine (TRANSPERS). She is a core faculty member in the UCSF Philip R. Lee Institute for Health Policy Studies and UCSF Helen Diller Family Comprehensive Cancer Center, and is affiliated with the Institute for Human Genetics, Department of Epidemiology and Biostatistics, Baker Computational Health Sciences Institute, and Global Health Sciences.