HuGENet Case Studies

This is an on-line presentation designed to sharpen your epidemiological skills and enhance your knowledge on genomic variation and human diseases.

Purpose

To train health professionals in the practical application of human genome epidemiology (HuGE), which translates gene discoveries to disease prevention by integrating population-based data on gene-disease relationships and interventions. Students will acquire conceptual and practical tools for critically evaluating the growing scientific literature in specific disease areas.

Instructions

Case studies are presented as follows:

1. Educational objectives
2. Case study
   • Overview about the topic
   • A summary of the information contained in each article
   • Questions and answers about the article
   • Workspace and an opportunity to submit your answer
   • Our answer key
3. Bibliography
4. Medline Search Opportunity

*Note: Although you may quit and resume at any time, it is important to read each case study in the order in which it is presented.

Case Studies

• Genetic associations with obesity
  November 2013
• Genetics, coffee consumption, and Parkinson’s disease
  January 2013
• Using Whole Genome Scans to Discover Obesity Genes: Implications for the Clinical Utility of Genetic Testing in Obesity
  July 2007
• Multiple genetic testing for susceptibility to common disease:PPARG and CAPN10 SNP’s and type 2 diabetes
  June 2006
• Evaluation of the TCF7L2 gene as a predictor of type 2 diabetes
  June 2006
• Glucocerebrosidase Gene Mutations and Parkinson Disease
  June 2005
• Fictional Scenario To Test Your Knowledge of Gene- Environment Interaction: Rheumatoid Arthritis, Herbal Supplements and Fictitious Rheumatoid Arthritis Gene
  August 2002
• NOD2 and Crohn disease
  December 2001
• Factor V Leiden and Venous Thrombosis
  December 2001