Part IV: CASE STUDIES: Using Human Genome Epidemiology Information to Improve Health Chapter 24 Figures

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Figure 24-1
Population-specific epidemiological data processing to GJB2 and nonsyndromic hearing loss. Contribution of GJB2 variants (35ΔG, 167ΔT, and 235ΔC) to nonsyndromic hearing loss in
United States
(White Americans) (37,55,57,59,66)
Europe (29-32)
Tunisia (42)
Israel (23,24)
Korea (33)
Japan (34-36)
Australia (60)
No variation
67%
59
82
50%
87
79
76%
35ΔG/35ΔG
16%
18
16
12
4
35ΔG/other
5%
5
4
35ΔG/unknown or 35ΔG/+
9%
16
2
6
2
6
35ΔG/167ΔT
0%
10
167ΔT/167ΔT or 167ΔT/other
2
1
18
167ΔT/+
0
2
235ΔC/235ΔC
0
4
8
235ΔC/other
0
4
8
2
235ΔC/+
0
1
2
Other/other
1
2
2
3
3
Other/+
0
1
5

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