Charles C. Shepard Science Awards Winners

2021

Assessment – National Center for Chronic Disease and Health Promotion

Adam S. Vaughan, Linda Schieb, and Michele Casper
Historic and recent trends in county-level coronary heart disease death rates by race, gender, and age group, United States, 1979-2017
PLoS One 2020;15(7):e0235839

Data Methods and Study Design – Center for Global Health

Andrew F. Auld, Katherine Fielding, Tefera Agizew, Alice Maida, Anikie Mathoma, Rosanna Boyd, Anand Date, Sherri L. Pals, George Bicego, Yuliang Liu, Ray W. Shiraishi, Peter Ehrenkranz, Christopher Serumola, Unami Mathebula, Heather Alexander, Salome Charalambous, Courtney Emerson, Goabaone Rankgoane-Pono, Pontsho Pono, Alyssa Finlay, James C. Shepherd, Charles Holmes, Tedd V. Ellerbrock, and Alison D. Grant
Risk scores for predicting early antiretroviral therapy mortality in sub-Saharan Africa to inform who needs intensification of care: a derivation and external validation cohort study
BMC Medicine 2020;18(1):311

Laboratory Science – National Center for Immunization and Respiratory Diseases

Jennifer L. Konopka-Anstadt, Ray Campagnoli, Annelet Vincent, Jing Shaw, Ling Wei, Nhien T. Wynn, Shane E. Smithee, Erika Bujaki, Ming Te Yeh, Majid Laassri, Tatiana Zagorodnyaya, Amy J. Weiner, Konstantin Chumakov, Raul Andino, Andrew Macadam, Olen Kew, and Cara C. Burns
Development of a new oral poliovirus vaccine for the eradication end game using codon deoptimization
Nature Partner Journals Vaccines 2020;5(1):26

Prevention and Control – Center for Global Health

Andrew F. Auld, Tefera Agizew, Anikie Mathoma, Rosanna Boyd, Anand Date, Sherri L. Pals, Christopher Serumola, Unami Mathebula, Heather Alexander, Tedd V. Ellerbrock, Goabaone Rankgoane-Pono, Pontsho Pono, James C. Shepherd, Katherine Fielding, Alison D. Grant, and Alyssa Finlay
Effect of tuberculosis screening and retention interventions on early antiretroviral therapy mortality in Botswana: a stepped-wedge cluster randomized trial
BMC Medicine 2020;18(1):19

Health Equity Science – National Center for Chronic Disease and Health Promotion

Xu Ji, Shanna Cox, Scott D. Grosse, Wanda D. Barfield, Brian S. Armour, Elizabeth A. Courtney-Long, and Rui Li
Association of smoke-free laws with preterm or low birth weight deliveries-A multistate analysis
Health Services Research 2021;56(1):61-72

Lifetime Scientific Achievement

Stuart Nichol, PhD
National Center for Emerging and Zoonotic Infectious Diseases

2020

Assessment (Co-winners)

Kathleen P. Hartnett, Aaron Kite-Powell, Megan T. Patel, Brittani L. Haag, Michael J. Sheppard, Taylor P. Dias, Brian A. King, Paul C. Melstrom, Matthew D. Ritchey, Zachary Stein, Nimi Idaikkadar, Alana M. Vivolo-Kantor, Dale A. Rose, Peter A. Briss, Jennifer E. Layden, Loren Rodgers, and Jennifer Adjemian
Syndromic Surveillance for E-Cigarette, or Vaping, Product Use-Associated Lung Injury
The New England Journal of Medicine 2020; 69(9):236-240

Lyna Z. Schieber, Gery P. Guy, Jr., Puja Seth, Randall Young, Christine L. Mattson, Christina A. Mikosz, and Richard A. Schieber
Trends and Patterns of Geographic Variation in Opioid Prescribing Practices by State, United States, 2006-2017
JAMA Network Open 2019; 2(3):e190665

Data Methods and Study Design

David S. Campo, Vishal Nayak, Ganesh Srinivasamoorthy and Yury Khudyakov
Entropy of mitochondrial DNA circulating in blood is associated with hepatocellular carcinoma
BMC Medical Genomics 2019; 12(Suppl 4):74

Laboratory Science

Patricia A. Jorquera, Vasiliy P. Mishin, Anton Chesnokov, Ha T. Nguyen, Brian Mann, Rebecca Garten, John Barnes, Erin Hodges, Juan De La Cruz, Xiyan Xu, Jackie Katz, David E. Wentworth and Larisa V. Gubareva

Insights into the antigenic advancement of influenza A(H3N2) viruses, 2011–2018
Scientific Reports 2019; 9:2676

Prevention and Control

Meng-Yu Chen, Charles E. Rose, Yan Ping Qi, Jennifer L. Williams, Lorraine F. Yeung, Robert J. Berry, Ling Hao, Michael J. Cannon, and Krista S. Crider

Defining the plasma folate concentration associated with the red blood cell folate concentration threshold for optimal neural tube defects prevention: a population-based, randomized trial of folic acid supplementation
American Journal of Clinical Nutrition 2019; 109:1452-1461

Lifetime Scientific Achievement

Dr. Jim Pirkle
National Center for Environmental Health/Agency for Toxic Substances and Disease Registry

2019

Assessment

Samir K Saha, Stephanie J Schrag Shams El Arifeen, Luke C Mullany, Mohammad Shahidul Islam, Nong Shang, Shamim A Qazi, Anita K M Zaidi, Zulfiqar A Bhutta, Anuradha Bose, Pinaki Panigrahi, Sajid B Soofi, Nicholas E Connor, Dipak K Mitra, Rita Isaac, Jonas M Winchell, Melissa L Arvay, Maksuda Islam, Yasir Shafiq, Imran Nisar, Benazir Baloch, Furqan Kabir, Murtaza Ali, Maureen H Diaz, Radhanath Satpathy, Pritish Nanda, Bijaya K Padhi, Sailajanandan Parida, Aneeta Hotwani, M Hasanuzzaman, Sheraz Ahmed, Mohammad Belal Hossain, Shabina Ariff, Imran Ahmed, Syed Mamun Ibne Moin, Arif Mahmud, Jessica L Waller, Iftekhar Rafiqullah, Mohammad A Quaiyum, Nazma Begum, Veeraraghavan Balaji, Jasmin Halen, A S M Nawshad Uddin Ahmed, Martin W Weber Davidson, H Hamer, Patricia L Hibberd, Qazi Sadeq-ur Rahman, Venkat Raghava Mogan, Tanvir Hossain, Lesley McGee, Shalini Anandan, Anran Liu, Kalpana Panigrahi, Asha Mary Abraham, and Abdullah H Baqui

Causes and incidence of community-acquired serious infections among young children in south Asia (ANISA): an observational cohort study
Lancet 2018; 392(10142): 145-159

Data Methods and Study Design

Diba Khana, Lauren M. Rossen, Holly Hedegaard, and Margaret Warner
A Bayesian Spatial Temporal Modeling Approach to Mapping Geographic Variation in Mortality Rates for Subnational areas with R-INLA
Journal of Data Science 2018; 16(1): 147-182

Laboratory Science

Markus H. Kainulainen, Jessica R. Spengler, Stephen R. Welch, JoAnn D. Coleman-McCray, Jessica R. Harmon, John D. Klena, Stuart T. Nichol, Cesar G. Albarino, and Christina F. Spiropoulou

Use of a Scalable Replicon-Particle Vaccine to Protect Against Lethal Lassa Virus Infection in the Guinea Pig Model
Journal of Infectious Diseases 2018; 217(12): 1957-1966

Prevention and Control

Khalequ Zaman, Concepcion F. Estivariz, Michelle Morales, Mohammad Yunus, Cynthia J. Snider, Howard E. Gary, Jr., William C. Weldon, M. Steven Oberste, Steven G. Wassilak, Mark A. Pallansch, and Abhijeet Anand

Immunogenicity of type 2 monovalent oral and inactivated poliovirus vaccines for type 2 poliovirus outbreak response: an open-label, randomized controlled trial
Lancet Infectious Diseases 2018; 18(6): 657-665

Lifetime Achievement

Rima F. Khabbaz, M.D.
NCEZID

2018

Assessment

A Danielle Iuliano, Katherine M. Roguski, Howard H. Chang, David J. Muscatello, Rakhee Palekar, Stefano Tempia, Cheryl Cohen, Jon Michael Gran, Dena Schanzer, Benjamin J. Cowling, Peng Wu, Jan Kyncl, Li Wei Ang, Minah Park, Monika Redlberger-Fritz, Hongjie Yu, Laura Espenhain, Anand Krishnan, Gideon Emukule, Liselotte van Asten, Susana Pereira da Silva, Suchunya Aungkulanon, Udo Buchholz, Marc-Alain Widdowson, Joseph S. Bresee, for the Global Seasonal Influenza-associated Mortality Collaborator Network

Estimates of global seasonal influenza-associated respiratory mortality: a modelling study
The Lancet 2018; 391:1285-1300

Data Methods and Study Design

Ellsworth M. Campbell, Hongwei Jia, Anupama Shankar, Debra Hanson, Wei Luo, Silvina Masciotra, S. Michele Owen, Alexandra M. Oster, Romeo R. Galang, Michael W. Spiller, Sara J. Blosser, Erika Chapman, Jeremy C. Roseberry, Jessica Gentry, Pamela Pontones, Joan Duwve, Paula Peyrani, Ron M. Kagan, Jeannette M. Whitcomb, Philip J. Peters, Walid Heneine, John T. Brooks, and William M. Switzer

Detailed Transmission Network Analysis of a Large Opiate-Driven Outbreak of HIV Infection in the United States
The Journal of Infectious Diseases 2017; 216:1053–62

Laboratory Science

Amrita Kumar, Jin Hyang Kim, Priya Ranjan, Maureen G. Metcalfe, Weiping Cao, Margarita Mishina, Shivaprakash Gangappa, Zhu Guo, Edward S. Boyden, Sherif Zaki, Ian York, Adolfo García-Sastre, Michael Shaw & Suryaprakash Sambhara

Influenza virus exploits tunneling nanotubes for cell-to-cell spread
Scientific Reports 2017; DOI: 10.1038/srep40360

Prevention and Control

Rahi Abouk, Scott D. Grosse, Elizabeth C. Ailes, Matthew E. Oster

Association of US State Implementation of Newborn Screening Policies for Critical Congenital Heart Disease With Early Infant Cardiac Deaths
JAMA 2017;318(21):2111-2118

Lifetime Achievement

Stephen L. Cochi, MD, MPH
Center for Global Health

2017

Assessment

Katherine E. Fleming-Dutra, Adam L. Hersh, Daniel J. Shapiro, Monina Bartoces, Eva A. Enns, Thomas M. File Jr., Jonathan A. Finkelstein, Jeffrey S. Gerber, David Y. Hyun, Jeffrey A. Linder, Ruth Lynfield, David J. Margolis, Larissa S. May, Daniel Merenstein, Joshua P. Metlay, Jason G. Newland, Jay F. Piccirillo, Rebecca M. Roberts, Guillermo V. Sanchez, Katie J. Suda, Ann Thomas, Teri Moser Woo, Rachel M. Zetts, and Lauri A. Hicks
Prevalence of Inappropriate Antibiotic Prescriptions Among US Ambulatory Care Visits, 2010-2011
Jama 2016;315(17):1864-73

Data Methods and Study Design

Samuel S. Shepard, Sarah Meno, Justin Bahl, Malania M. Wilson, John Barnes, and Elizabeth Neuhaus
Viral deep sequencing needs an adaptive approach: IRMA, the iterative refinement meta-assembler
BMC Genomics 2016;17:708

Laboratory and Methods

Sabine M. G. van der Sanden, Weilin Wu, Naomi Dybdahl-Sissoko, William C. Weldon, Paula Brooks, Jason O’Donnell, Les P. Jones, Cedric Brown, S. Mark Tompkins, M. Steven Oberste, Jon Karpilow, and Ralph A. Tripp
Engineering Enhanced Vaccine Cell Lines To Eradicate Vaccine-Preventable Diseases: the Polio End Game
Journal of Virology 2016;90(4):1694-704

Prevention and Control

Philip J. Peters, Pamela Pontones, Karen W. Hoover, Monita R. Patel, Romeo R. Galang, Jessica Shields, Sara J. Blosser, Michael W. Spiller, Brittany Combs, William M. Switzer, Caitlin Conrad, Jessica Gentry, Yury Khudyakov, Dorothy Waterhouse, S. Michele Owen, Erika Chapman, Jeremy C. Roseberry, Veronica McCants, Paul J. Weidle, Dita Broz, Taraz Samandari, Jonathan Mermin, Jennifer Walthall, John T. Brooks, Joan M. Duwve, for the HIV Outbreak Investigation Team Indiana
HIV Infection Linked to Injection Use of Oxymorphone in Indiana, 2014-2015
The New England Journal of Medicine 2016;375(3):229-39

Lifetime Scientific Achievement

Patrick J. Lammie, PhD
Center for Global Health, Division of Parasitic Diseases and Malaria

2016

Assessment

Alexandra M. Oster, Joel O. Wertheim, Angela L. Hernandez, Marie Cheryl Bañez Ocfemia, Neeraja Saduvala, and H. Irene Hall
Using Molecular HIV Surveillance Data to Understand Transmission Between Subpopulations in the United States
Journal of Acquired Immune Deficiency Syndromes 2015;70:444–451

Data Methods and Study Design

Jacek Skarbinski, Eli Rosenberg, Gabriela Paz-Bailey, H. Irene Hall, Charles E. Rose, Abigail H. Viall, Jennifer L. Fagan, Amy Lansky, Jonathan H. Mermin
Human Immunodeficiency Virus Transmission at Each Step of the Care Continuum in the United States
JAMA Internal Medicine 2015;175(4):588-96

Laboratory and Methods

David S. Campo, Guo-Liang Xia, Zoya Dimitrova, Yulin Lin, Joseph C. Forbi, Lilia Ganova-Raeva, Lili Punkova, Sumathi Ramachandran, Hong Thai, Pavel Skums, Seth Sims, Inna Rytsareva, Gilberto Vaughan, Ha-Jung Roh, Michael A. Purdy, Amanda Sue, and Yury Khudyakov
Accurate Genetic Detection of Hepatitis C Virus Transmissions in Outbreak Settings
The Journal of Infectious Diseases 2015;213(6):957-965

Prevention and Control

Concepción F. Estívariz, Abhijeet Anand, Howard E. Gary Jr., Mahmudur Rahman, Jannatul Islam, Tajul I. Bari, Steven G.F. Wassilak, Susan Y. Chu, William C. Weldon, Mark A. Pallansch, James D. Heffelfinger, Stephen P. Luby, Khalequ Zaman
Immunogenicity of three doses of bivalent, trivalent, or type 1 monovalent oral poliovirus vaccines with a 2 week interval between doses in Bangladesh: an open-label, non-inferiority, randomised, controlled trial
Lancet Infectious Diseases 2015;15:898–904

Lifetime Scientific Achievement

RADM Kenneth Gabriel Castro, MD
National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention

2015

Assessment

Shelley S. Magill, Jonathan R. Edwards, Wendy Bamberg, Zintars G. Beldavs, Ghinwa Dumyati, Marion A. Kainer, Ruth Lynfield, Meghan Maloney, Laura McAllister-Hollod, Joelle Nadle, Susan M. Ray, Deborah L. Thompson, Lucy E. Wilson, and Scott K. Fridkin, for the Emerging Infections Program Healthcare-Associated Infections and Antimicrobial Use Prevalence Survey Team*
Multistate Point-Prevalence Survey of Health Care–Associated Infections
The New England Journal of Medicine 2014; 370(13):1198–1208

Data Methods and Study Design

Krista S. Crider, Owen Devine, Ling Hao, Nicole F. Dowling, Song Li, Anne M. Molloy, Zhu Li, Jianghui Zhu, and Robert J. Berry
Population Red Blood Cell Folate Concentrations for Prevention of Neural Tube Defects: Bayesian Model
BMJ (clinical research edition) 2014;349:g4554

Laboratory and Methods

Hua Yang, Jessie C. Chang, Zhu Guo, Paul J. Carney, David A. Shore, Ruben O. Donis, Nancy J. Cox, Julie M. Villanueva, Alexander I. Klimov, and James Stevens
Structural Stability of Influenza A(H1N1)pdm09 Virus Hemagglutinins
Journal of Virology 2014;88(9):4828–4838

Prevention and Control

The RTS,S Clinical Trials Partnership
Efficacy and Safety of the RTS,S/AS01 Malaria Vaccine During 18 Months After
Vaccination: A Phase 3 Randomized, Controlled Trial in Children and Young Infants at 11 African Sites

PLoS Medicine 2014;11(7):e1001685

Lifetime Scientific Achievement

Patricia M. Griffin, MD
National Center for Emerging and Zoonotic Infectious Diseases

2014

Assessment

Nadira K. Sultana, Samir K. Saha, Hassan M. Al-Emran, Joyanta K. Modak, M. A. Yushuf Sharker, Shams El-Arifeen, Adam L. Cohen, Abdullah H. Baqui, and Stephen P. Luby
Impact of Introduction of the Haemophilus influenzae Type b Conjugate Vaccine into Childhood Immunization on Meningitis in Bangladeshi Infants

Prevention and Control

Tim McAfee, Kevin C Davis, Robert L Alexander Jr, Terry F Pechacek, Rebecca Bunnell
Effect of the first federally funded U.S. antismoking national media campaign

Laboratory Science

James M. Smith, Rachna Rastogi, Ryan S. Teller, Priya Srinivasan, Pedro M. M. Mesquita, Umadevi Nagaraja, Janet M. McNicholl, R. Michael Hendry, Chuong T. Dinh, Amy Martin, Betsy C. Herold, and Patrick F. Kiser
Intravaginal ring eluting tenofovir disoproxil fumarate completely protects macaques from multiple vaginal simian-HIV challenges

Data Methods and Study Design

Matthew W. Wheeler, A. John Bailer
An empirical comparison of low-dose extrapolation from points of departure (PoD) compared to extrapolations based upon methods that account for model uncertainty

Lifetime Scientific Achievement

Nancy J. Cox, PhD
National Center for Immunization and Respiratory Diseases

2013

Assessment

Rachel M. Smith, M.D., M.P.H., Melissa K. Schaefer, M.D., Marion A. Kainer, M.B., B.S., M.P.H., Matthew Wise, Ph.D., Jennie Finks, D.V.M., M.V.P.H., Joan Duwve, M.D., M.P.H., Elizabeth Fontaine, M.S.P.H., Alvina Chu, M.H.S., Barbara Carothers, L.P.N., Amy Reilly, R.N., Jay Fiedler, M.S., Andrew D. Wiese, M.P.H., Christine Feaster, R.M., Lex Gibson, B.S., Stephanie Griese, M.D., Anne Purfield, Ph.D., Angela A. Cleveland, M.P.H., Kaitlin Benedict, M.P.H., Julie R. Harris, Ph.D., M.P.H., Mary E. Brandt, Ph.D., Dianna Blau, D.V.M., Ph.D., John Jernigan, M.D., J. Todd Weber, M.D., and Benjamin J. Park, M.D., for the Multistate Fungal Infection Outbreak Response Team
Immunogenicity of Supplemental Doses of Poliovirus Vaccine for Children Aged 6-9 Months in Moradabad, India: A Community-Based, Randomized Controlled Trial

Prevention and Control

Ryan T Novak, Jean Ludovic Kambou, Fabien V K Diomandé, Tiga F Tarbangdo, Rasmata Ouédraogo-Traoré, Lassana Sangaré, Clement Lingani, Stacey W Martin, Cynthia Hatcher, Leonard W Mayer, F Marc LaForce, Fenella Avokey, Mamoudou H Djingarey, Nancy E Messonnier, Sylvestre R Tiendrébéogo, Thomas A Clark
Author Ryan T. Novak, paper Serogroup A meningococcal conjugate vaccination in Burkina Faso: analysis of national surveillance data.

Laboratory Science

Yen T. Duong, Maofeng Qiu, Anindya K. De, Keisha Jackson, Trudy Dobbs, Andrea A. Kim, John N. Nkengasong, Bharat S. Parekh
Author Yen T. Duong, Detection of Recent HIV-1 Using a New Infection Limiting-Antigen Avidity Assay: Potential for HIV-1 Incidence Estimates and Avidity Maturation Studies.

Data Methods and Study Design

Joseph Y. Abrams, John R. Copeland, Robert V. Tauxe, Kashmira A. Date, Ermias D. Belay, Rajal K. Mody, and Eric D. Mintz
Author Abrams, J.Y., et. al., “Real-time modeling used for outbreak management during a cholera epidemic, Haiti, 2010-2011”

Lifetime Scientific Achievement

Larry J. Anderson, MD
National Center for Immunization and Respiratory Diseases

2012

Laboratory Science

Brian H. Bird, Louis H. Maartens, Shelley Campbell, Baltus J. Erasmus, Bobbie R. Erickson, Kimberly A. Dodd, Christina F. Spiropoulou, Deborah Cannon, Clifton P. Drew, Barbara Knust, Anita K. McElroy, Marina L. Khristova, César G. Albariño, and Stuart T. Nichol
Rift Valley Fever Virus Vaccine Lacking the NSs and NSm Genes Is Safe, Nonteratogenic, and Confers Protection from Virema, Pyrexia, and Abortion following Challenge in Adult and Pregnant Sheep
Journal of Virology 2011; 85(24):12901-12909

Data Methods and Study Design

Alula Hadgu, Nandini Dendukuri, and Liangliang Wang
Evaluation of Screening Tests for Detecting Chlamydia trachomatis Bias Associated with the Patient-Infected-Status Algorithm Epidemiology
2012; 23(1):72-82 (published online 2011)

Assessment

Concepción F. Estívariz, Hamid Jafari, Roland W. Sutter, T. Jacob John, Vibhor Jain, Ashutosh Agarwal, Harish Verma, Mark A Pallansch, Ajit P. Singh, Sherine Guirguis, Jitendra Awale, Anthony Burton, Sunil Bahl, Arani Chatterjee, and R. Bruce Aylward
Immunogenicity of Supplemental Doses of Poliovirus Vaccine for Children Aged 6-9 Months in Moradabad, India: A Community-Based, Randomized Controlled Trial
The Lancet Infectious Diseases 2012;12(2):128-135 (published online 2011)

Prevention and Control

Timothy R. Sterling, M. Elsa Villarino, Andrey S. Borisov, Nong Shang, Fred Gordin, Erin Bliven-Sizemore, Judith Hackman, Carol Dukes Hamilton, Dick Menzies, Amy Kerrigan, Stephen E. Weis, Marc Weiner, Diane Wing, Marcus B. Conde, Lorna Bozeman, C. Robert Horsburgh, and Richard E. Chaisson for the TB Trials Consortium PREVENT TB Study Team
Three Months of Rifapentine and Isoniazid for Latent Tuberculosis Infection
New England Journal of Medicine 2011;365(23):2155–2166

Lifetime Scientific Achievement

Henry Falk, MD, MPH
National Center for Environmental Health/Agency for Toxic Substances and Disease Registry

2011

Assessment and Epidemiology

Stacy M. Holzbauer, Aaron S. DeVries, James J. Sejvar, Christine H. Lees, Jennifer Adjemian, Jennifer H. McQuiston, Carlota Medus, Catherine A. Lexau, Julie R. Harris, Sergio E. Recuenco, Ermias D. Belay, James F. Howell, Bryan F. Buss, Mady Hornig, John D. Gibbins, Scott E. Brueck, Kirk E. Smith, Richard N. Danila, W. Ian Lipkin, Daniel H. Lachance, P. James B. Dyck, and Ruth Lynfield
Epidemiologic Investigation of Immune-Mediated Polyradiculoneuropathy among
Abattoir Workers Exposed to Porcine Brain

PLoS One 2010;5(3):e9782

Laboratory and Methods

Robert D. Gilmore, Jr., Rebekah R. Howison, Gabrielle Dietrich, Toni G. Patton, Dawn R. Clifton, and James A. Carroll
The bba64 Gene of Borrelia burgdorferi, the Lyme Disease Agent, Is Critical for
Mammalian Infection via Tick Bite Transmission

Proceedings of the National Academy of Sciences of the United States of America 2010;107(16):7515–7520

Prevention and Control

Charles S. Chasela, Michael G. Hudgens, Denise J. Jamieson, Dumbani Kayira, Mina C. Hosseinipour, Athena P. Kourtis, Francis Martinson, Gerald Tegha, Rodney J. Knight, Yusuf I. Ahmed, Deborah D. Kamwendo, Irving F. Hoffman, Sascha R. Ellington, Zebrone Kacheche, Alice Soko, Jeffrey B. Wiener, Susan A. Fiscus, Peter Kazembe, Innocent A. Mofolo, Maggie Chigwenembe, Dorothy S. Sichali, and Charles M. van der Horst; for the Breastfeeding, Antiretroviral, and Nutrition study group
Maternal or Infant Antiretroviral Drugs to Reduce HIV-1 Transmission
New England Journal of Medicine 2010;362(24):2271–2281

Lifetime Scientific Achievement

Kathleen Kreiss, MD

Dr. Kreiss was recognized as a world-renowned expert in occupational respiratory disease. She has improved workplace safety by encouraging the use of safer materials and better work practices and controls.

2010

Assessment and Epidemiology

Fatimah S. Dawood, Seema Jain, Lyn Finelli, Michael W. Shaw, Stephen Lindstrom, Rebecca J. Garten, Larisa V. Gubareva, Xiyan Xu, Carolyn B. Bridges, and Timothy M. Uyeki
Emergence of a Novel Swine–Origin Influenza A (H1N1) Virus in Humans
New England Journal of Medicine 360; 25

Prevention and Control

Manish Patel, Cristina Pedreira, Lucia Helena De Oliveira, Jacqueline Tate, Maribel Orozco, Juan Mercado, Alcides Gonzalez, Omar Malespin, Juan Jose´ Amador, Jazmina Uman˜ a, Angel Balmaseda, Maria Celina Perez, Jon Gentsch, Tara Kerin, Jennifer Hull, Slavica Mijatovic, Jon Andrus, Umesh Parashar
“Association between Pentavalent Rotavirus Vaccine and Severe Rotavirus Diarrhea among Children in Nicaragua”
JAMA 2009; 301(21):2243–2251

Sandra L. Decker
Changes in Medicaid Physician Fees and Patterns of Ambulatory Care
Inquiry 2009; 46(3) 291–304

Laboratory and Methods

Joseph U. Igietseme, Qing He, Kahaliah Joseph, Francis O. Eko, Deborah Lyn, Godwin Ananaba, Angela Campbell, Claudiu Bandea, and Carolyn M. Black
“Role of T Lymphocytes in the Pathogenesis of Chlamydia Disease”
The Journal of Infectious Diseases 2009; 200:926–34

Lifetime Scientific Achievement

Polly Marchbanks, MSN, PhD
National Center for Chronic Disease Prevention and Health Promotion

2009

Assessment and Epidemiology

H. Irene Hall, R. Song, P. Rhodes, J. Prejean, Q. An, L. Lee, J. Karon, R. Brookmeyer, E. Kaplan, M. McKenna, R. Janssen,
“Estimation of HIV Incidence in the United States”
JAMA, 2008;300(5):520–529 (doi:10.1001/jama.300.5.520)

Laboratory and Methods

T. Williams, L. Luna, Z. Guo, N. Cox, J. Pirkle, R. Donis, J. Barr
“Quantification of influenza virus hemagglutinins in complex mixtures using isotope dilution tandem mass spectrometry”
Vaccine (2008) 26, 2510–2520 (doi:10.1016/j. vaccine.2008.03.014)

Prevention and Control

L. Roux, M. Pratt, T. Tengs, M. Yore, T. Yanagawa, J. Van Den Bos, C. Rutt, R. Brownson, K. Powell, G. Heath, H. Kohl, S. Teutsch, J. Cawley, I-Min Lee, L. West, D. Buchner
“Cost Effectiveness of Community-Based Physical Activity Interventions”
Am J Prev Med, 2008;35 (6) (doi:10.1016/j.amepre.2008.06.040)

Lifetime Scientific Achievement

Stephen B. Thacker, M.D.
Office of the Director, Office of Workforce and Career Development

2008

Assessment and Epidemiology

Earl S. Ford, Umed A. Ajani, Janet B. Croft, Julia A. Critchley, Darwin R. Labarthe, Thomas E. Kottke, Wayne H. Giles, and Simon Capewell
“Explaining the Decrease in U.S. Deaths from Coronary Disease, 1980–2000”
The New England Journal of Medicine 2007;356:2388–2398

Laboratory and Methods

Terrence M. Tumpey, Taronna R. Maines, Neal Van Hoeven, Laurel Glaser, Alicia Solórzano, Claudia Pappas, Nancy J. Cox, David E. Swayne, Peter Palese, Jacqueline M. Katz, and Adolfo García–Sastre
“A Two-Amino Acid Change in the Hemagglutinin of the 1918 Influenza Virus Abolishes Transmission”
Science 2007; 315:655–659

Prevention and Control

R. Louise Floyd, Mark Sobell, Mary M. Velasquez, Karen Ingersoll, Mary Nettleman, Linda Sobell, Patricia Dolan Mullen, Sherry Ceperich, Kirk von Sternberg, Burt Bolton, Bradley Skarpness, Kenneth Johnson, and Jyothi Nagaraja, on behalf of the Project CHOICES Efficacy Study Group
“Preventing Alcohol-Exposed Pregnancies. A Randomized Controlled Trial”
American Journal of Preventive Medicine 2007;32:1–10

Lifetime Scientific Achievement

Vincent Castranova, PhD
National Institute for Occupational Safety and Health

2007

Assessment and Epidemiology

Wolfgang Hladik, Shelia C. Dollard, Jonathan Mermin, Ashley L. Fowlkes, Robert Downing, Minal M. Amin, Flora Banage, Esau Nzaro, Peter Kataaha, Timothy J. Dondero, Philip E. Pellett, and Eve M. Lackritz
Transmission of Human Herpesvirus 8 by Blood Transfusion
The New England Journal of Medicine 2006;355:1331–1338

Laboratory and Methods

Mary A. Hoelscher, Sanjay Garg, Dinesh S. Bangari, Jessica A. Belser, Xiuhua Lu, Iain Stephenson, Rick A. Bright, Jacqueline M. Katz, Suresh K. Mittal, and Suryaprakash Sambhara
Development of Adenoviral-Vector-Based Pandemic Influenza Vaccine Against Antigenically Distinct Human H5N1 Strains in Mice
The Lancet 2006;367;475–481

Prevention and Control

Cynthia G. Whitney, Tamar Pilishvili, Monica M. Farley, William Schaffner, Allen S. Craig, Ruth Lynfield, Ann-Christine Nyquist, Kenneth A. Gershman, Marietta Vazquez, Nancy M. Bennett, Arthur Reingold, Ann Thomas, Mary P. Glode, Elizabeth R. Zell, James H. Jorgensen, Bernard Beall, and Ann Schuchat
Effectiveness of Seven-Valent Pneumococcal Conjugate Vaccine Against Invasive Pneumococcal Disease: A Matched Case-Control Study
The Lancet 2006;368:1495–1502

Lifetime Scientific Achievement

Roger I. Glass, M.D., M.P.H., Ph.D.

2006

Assessment and Epidemiology

Katherine M. Flegal, Barry I. Graubard, David F. Williamson, and Mitchell H. Gail Excess Deaths Associated With Underweight, Overweight, and Obesity
JAMA 2005;293:1861–1867.

Lee Warner, Maurizio Macaluso, Harland D. Austin, David K. Kleinbaum, Lynn Artz,
Michael E. Fleenor, Ilene Brill, Daniel R. Newman, and Edward W. Hook, III
Application of the Case-Crossover Design to Reduce Unmeasured Confounding in Studies of Condom Effectiveness American Journal of Epidemiology 2005;161:765–773.

Laboratory and Methods

Terrence M. Tumpey, Christopher F. Basler, Patricia V. Aguilar, Hui Zeng, Alicia Solorzano, David E. Swayne, Nancy J. Cox, Jacqueline M. Katz, Jeffery K. Taubenberger, Peter Palese, Adolfo Garcia-Sastre
Characterization of the Reconstructed 1918 Spanish Influenza Pandemic Virus.
Science 2005; 310(5745); 77–80.

Prevention and Control

Stephen P. Luby, Mubina Agboatwalla, Daniel R Feikin, John Painter, Ward Billhimer, Arshad Altaf, and Robert M. Hoekstra.
Effect of handwashing on child health: a randomised controlled trial.
The Lancet 2005;366:225–233.

Lifetime Scientific Achievement

Robert V. Tauxe, M.D., M.P.H.

2005

Assessment and Epidemiology

Barbara Lopes Cardozo, Oleg O. Bilukha, Carol A. Gotway Crawford, Irshad Shaikh, Mitchell I. Wolfe, Michael L. Gerber, and Mark Anderson
Mental Health, Social Functioning, and Disability in Postwar Afghanistan
JAMA 292:575–84

Laboratory and Methods

Justin M. Hettick, Michael L. Kashon, Janet P. Simpson, Paul D. Siegel, Gerald H. Mazurek, and David N. Weissman
Proteomic Profiling of Intact Mycobacteria by Matrix-Assisted Laser Desorption/Ionization Time–of–Flight Mass Spectrometry
Analytical Chemistry 2004; 76:5769–5776

Prevention and Control

Marc Bulterys, Denise J. Jamieson, Mary Jo O’Sullivan, Mardge H. Cohen, Robert Maupin, Steven Nesheim, Maryis P. Webber, Russell Van Dyke, Jeffrey Wiener, Bernard M. Branson, for the Mother-Infant Rapid Intervention at Delivery (MIRIAD) Study Group
Rapid HIV-1 Testing during Labor: A Multicenter Study
JAMA 2004; 292:219–23

Outstanding Scientific Contribution to Public Health

William H. Hannon, Barbara W. Adams, and Robert F. Vogt
Newborn Screening Quality Assurance Program
National Center for Environmental Health/Agency for Toxic Substances and Disease Registry

Lifetime Scientific Achievement

James M. Hughes, M.D.
Dr. Hughes was recognized for his expertise infectious diseases and bioterrorism and response. His leadership and efforts to address emerging and reemerging global threats have brought global prominence to CDC and improved public health infrastructures nationwide.

2004

Assessment and Epidemiology

Jennita Reefhuis, Margaret A. Honein, Cynthia G. Whitney, Shadi Chamany, Eric A. Mann, Krista R. Biernath, Karen Broder, Susan Manning, Swati Avashia, Marcia Victor, Pamela Costa, Owen Devine, Ann Graham, and Coleen Boyle
Risk of Bacterial Meningitis in Children with Cochlear Implants
The New England Journal of Medicine 2003; 349:435–445

Laboratory and Methods

Thomas G. Ksiazek, Dean Erdman, Cynthia S. Goldsmith, Sherif R. Zaki, Teresa Peret, Shannon Emery, Suxiang Tong, Carlo Urbani, James A. Comer, Wilina Lim, Pierre E. Rollin, Scott F. Dowell, Ai-Ee Ling, Charles D. Humphrey, Wun-Ju Shieh, Jeannette Guarner, Christopher D. Paddock, Paul Rota, Barry Fields, Joseph DeRisi, Jyh-Yuan Yang, Nancy Cox, James M. Hughes, James W. LeDuc, William J. Bellini, Larry J. Anderson, and the SARS Working Group
A Novel Coronavirus Associated with Severe Acute Respiratory Syndrome
The New England Journal of Medicine 2003; 348:1953–1966

Prevention and Control

Cynthia G. Whitney, Monica M. Farley, James Hadler, Lee H. Harrison, Nancy M. Bennett, Ruth Lynfield, Arthur Reingold, Paul R. Cieslak, Tamara Pilishvili, Delois Jackson, Richard R. Facklam, James H. Jorgensen, and Anne Schuchat, for the Active Bacterial Core Surveillance of the Emerging Infections Program Network

Decline in Invasive Pneumococcal Disease after the Introduction of Protein–Polysaccharide Conjugate Vaccine
The New England Journal of Medicine 2003; 348:1737–1746

Outstanding Scientific Contribution to Public Health

National Health and Nutrition Examination Surveys (NHANES) Program

National Center for Health Statistics

Rosemarie Hirsch, Clifford Johnson, and Geraldine McQuillan

Lifetime Scientific Achievement (joint winners)

Harold W. Jaffe, M.D.
Dr. Jaffe was recognized as a national and international leader of the disease investigation of HIV/AIDS. His groundbreaking research includes the first national case–control study of AIDS, the first study showing that Kaposi’s sarcoma was caused by infection, the first cohort study to define the natural history of HIV infection, and the first study establishing a case of HIV transmission from a health care worker to a patient. His work has profoundly influenced scientific knowledge about HIV/AIDS, affecting national and international approaches to prevention and control.

Walter A. Orenstein, M.D.
Dr. Orenstein was recognized for his leadership in reducing the occurrence of vaccine–preventable diseases in children. His work has been critical to the development of national vaccine policy and global immunization strategies. Among the many accomplishments attributable to his leadership are the elimination of indigenous measles in the United States, the introduction of five vaccines for routine use, the development of a national surveillance system for the immunization of preschool children, and progress in global polio eradication and measles control.

2003

Assessment and Epidemiology

Polly A. Marchbanks, Jill A. McDonald, Hoyt G. Wilson, Suzanne G. Folger, Michele G. Mandel, Janet R. Daling, Leslie Bernstein, Kathleen E. Malone, Giske Ursin, Brian L. Strom, Sandra A. Norman, Linda K. Weiss, Phyllis Wingo, Michael S. Simon, Ronald T. Burkman, Jesse A. Berlin, and Robert Spirtas
Oral Contraceptives and the Risk of Breast Cancer
The New England Journal of Medicine 2002; 346:2025–2032

Laboratory and Methods

Bharat S. Parekh, M. Susan Kennedy, Trudy Dobbs, Chou-Pong Pau, Robert Byers, Timothy Green, Dale J. Hu, Suphak Vanichseni, Nancy L. Young, Kachit Choopanya, Timothy D. Mastro, and J. Steven McDougal
Quantitative Detection of Increasing HIV Type 1 Antibodies after Seroconversion: A Simple Assay for Detecting Recent HIV Infection and Estimating Incidence
AIDS Research and Human Retroviruses 2002; 18:295–307

Prevention and Control

Robert E. Quick, Akiko C. Kimura, Angelica Thevos, Mathias Tembo, Isidore Shamputa, Lori Hutwagner, and Eric Mintz
Diarrhea Prevention through Household-Level Water Disinfection and Safe Storage in Zambia
The American Journal of Tropical Medicine and Hygiene 2002; 66:584–589

Outstanding Scientific Contribution to Public Health

Barbara Lopes Cardozo, Bradley A. Woodruff, Muireann Brennan, and Paul B. Spiegel
International Emergency and Refugee Health Branch (IERHB)
National Center for Environmental Health

Lifetime Scientific Achievement

William R. Jarvis, M.D.
Dr. Jarvis was recognized as a leader in the study of nosocomial infections and other threats to the safety of both patients and health care workers, including those posed by antibiotic–resistant bacteria and by contaminated or improperly used medications, therapeutic agents, and medical devices. His research and collaboration with partners worldwide led to the implementation of numerous effective interventions to reduce these risks and to the development of prevention guidelines that serve as a basis for infection control programs throughout the world.

2002

Assessment and Epidemiology

Trudy V. Murphy, Paul M. Gargiulio, Mehran S. Massoudi, David B. Nelson, Aisha O. Jumaan, Catherine A. Okoro, Lynn R. Zanardi, Sabeena Setia, Elizabeth Fair, Charles W. LeBaron, Melinda Wharton, John R. Livengood, and Benjamin Schwartz, for the Rotavirus Intussusception Inspection Team
Intussusception among Infants Given an Oral Rotavirus Vaccine
The New England Journal of Medicine2001; 344:564–572

Laboratory and Methods

Brent S. Davis, Gwong-Jen J. Chang, Bruce Cropp, John T. Roehrig, Denise A. Martin, Carl J. Mitchell, Richard Bowen, and Michel L. Bunning
West Nile Virus Recombinant DNA Vaccine Protects Mouse and Horse from Virus Challenge and Expresses in Vitro a Noninfectious Recombinant Antigen That Can Be Used in Enzyme–Linked Immunosorbent Assays
Journal of Virology 2001; 75:4040–4047

Prevention and Control

Belinda E. Ostrowsky, William E. Trick, Annette H. Sohn, Stephen B. Quirk, Stacey Holt, Loretta A. Carson, Bertha C. Hill, Matthew J. Arduino, Matthew J. Kuehnert, and William R. Jarvis

Control of Vancomycin-Resistant Enterococcus in Health Care Facilities in a Region
The New England Journal of Medicine2001; 344:1427–1433

Outstanding Scientific Contribution to Public Health

Ronald M. Davis, Gary A. Giovino, Michael D. Erikson, and the Office on Smoking and Health
Surgeon General’s Reports on Smoking and Health
National Center for Chronic Disease Prevention and Health Promotion

Lifetime Scientific Achievement

Gerald R. Cooper, M.D., Ph.D.
Dr. Cooper was recognized for his leadership in improving laboratory measures of lipids that led to the establishment of the CDC Lipid Standardization Program.

2001

Assessment and Epidemiology

Paul B. Spiegel, Peter Salama
War and Mortality in Kosova, 1998–99: An Epidemiological Testimony
The Lancet 2000;335:2204–9

Prevention and Control

Carolyn Buxton Bridges, William W. Thompson, Martin I. Meltzer, Gordon R. Reeve, Walter J. Talamonti, Nancy J. Cox, Heather A. Lilac, Henrietta Hall, Alexander Klimov, Keiji Fukuda
Effectiveness And Cost-Benefit Of Influenza Vaccination Of Healthy Working Adults: A Randomized Controlled Trial
Journal Of The American Medical Association 2000;284:1655–62

Laboratory and Methods

K.B. Chua, W.J. Bellini, P.A. Rota, B.H. Harcourt, A. Tamin, S.K. Lam, T.G. Ksiazek P.E. Rollin, S.R. Zaki, W.J. Shieh, C.S. Goldsmith, D.J. Gubler, J.T. Roehrig, B. Eaton, A.R. Gould, J. Olson, H. Field, P. Daniels, A.E. Ling, C.J. Peters, L.J. Anderson, B.W.J. Mahy
Nipah Virus: A Recently Emergent Deadly Paramyxovirus
Science 2000;288:1432–1435

Outstanding Scientific Contributions to Public Health

Behavioral Risk Factor Surveillance System
National Center for Chromic Disease Prevention and Health Promotion

Lifetime Scientific Achievement

Joseph E. McDade, Ph.D.

2000

Nathan Shaffer, Rutt Chuachoowong, Philip A. Mock, Chaiporn Bhadrakom, Wimol Siriwasin, Nancy L. Young, Tawee Chotpitayasunondh, Sanay Chearskul, Anuvant Roongpisuthipong, Pratharn Chinayon, John Karon, Timothy D. Mastro, R.J. Simond
Shor–course zidovudine for perinatal HIV–1 transmission in Bangkok, Thailand: a randomised controlled trial
Lancet 1999;353: 773–780

1999

Robert S. Janssen, Glen A. Satten, Susan L. Stramer, Bhupat D. Rawal, Thomas R. O’Brien, Barbara J. Weiblen, Frederick M. Hecht, Noreen Jack, Farley R. Cleghorn, James O. Kahn, Margaret A. Chesney, Michael P. Busch
New Testing Strategy to Detect Early HIV–1 Infection for Use in Incidence Estimates and for Clinical and Prevention Purposes
Journal of the American Medical Association 1998;280(1);42–48.

Mary L. Kamb, Martin Fishbein, John M. Douglas, Fen Rhodes, Judy Rogers, Gail Bolan, Jonathan Zenilman, Tamara Hoxworth, Kevin Malotte, Michael Latesta, Charlotte Kent, Andrew Lentz, Sandra Graziano, Robert H. Byers, Thomas A. Peterman, for the Project RESPECT Study Group
Efficacy of Risk–Reduction Counseling to Prevent Human Immunodeficiency Virus and Sexually Transmitted Diseases
Journal of the American Medical Association1998;280(13):1161–67.

1998

Denise M. Cardo, David H. Culver, Carol A. Ciesielski, Pamela U. Srivastava, Ruthanne Marcus, Dominique Abiteboul, Julia Heptonstall, Giuseppe Ippolito, Florence Lot, Penny S. McKibben, David M. Bell and the Centers for Disease Control and Prevention Needlestick Surveillance Group
A Case–Control Study of HIV Seroconversion in Health Care Workers After Percutaneous Exposure
The New England Journal of Medicine 1997;337(21):1485–1490

1997

Jennifer S. Rota, Janet L. Heath, Paul A. Rota, Gail E. King*, María L. Celma, Juan Carabaña, Rafael Fernandez–Muñoz, David Brown, Li Jin, William J. Bellini
Molecular Epidemiology of Measles Virus: Identification of Pathways of Transmission and Implications for Measles Elimination
Journal of Infectious Diseases1996;173:32–7

Diana E. Schendel, Cynthia J. Berg, Marshalyn Yeargin–Allsopp, Coleen A. Boyle, Pierre Decoufle
Prenatal Magnesium Sulfate Exposure and the Risk for Cerebral Palsy or Mental Retardation Among Very Low–Birth–Weight Children Aged 3 to 5 Years.
Journal of the American Medical Association 1996;276:1805–10

1996

Peter M. Strebel, Nicolae Ion-Nedelcu, Andrew L. Baughman, Roland W. Sutter, Stephen L. Cochi
Intramuscular Injections Within 30 Days of Immunization with Oral Poliovirus Vaccine—A Risk Factor for Vaccine–Associated Paralytic Poliomyelitis.
New England Journal of Medicine 1995;332:500–6

1995

Robert D. Brewer, Peter D. Morris, Thomas B. Cole, Stephanie Watkins, Michael J. Patetta, Carol Popkin
The Risk of Dying in Alcohol–Related Automobile Crashes Among Habitual Drunk Drivers.
New England Journal of Medicine 1994;331:513–7

1994

Michael E. St. Louis, Munkolenkole Kamenga, Christopher Brown, Ann Marie Nelson, Tarande Manzila, Veronique Batter, Frieda Behets, Uwa Kabagabo, Robert W. Ryder, Margaret Oxtoby, Thomas C. Quinn, William L. Heyward.
Risk for Perinatal HIV–1 Transmission According to Maternal Immunologic, Virologic, and Placental Factors.
Journal of the American Medical Association 1993;269:2853–9

1993

Brian R. Edlin, Jerome I. Tokars, Michael H. Grieco, Jack T. Crawford, Julie Williams, Emelia M. Sordillo, Kenneth R. Ong, James O. Kilburn, Samuel W. Dooley, Kenneth G. Castro, William R. Jarvis, Scott D. Holmberg
An Outbreak of Multidrug–Resistant Tuberculosis Among Hospitalized Patients with the Acquired Immunodeficiency Syndrome.
New England Journal of Medicine 1992;326:1514–21

1992

Marta Gwinn, Marguierite Pappaioanou, J. Richard George, W. Harry Hannon, Shari C. Wasser, Martha A. Redus, Rodney Hoff, George F. Grady, Anne Willoughby, Antonia C. Novello, Lyle R. Petersen, Timothy J. Dondero, James W. Curran
Prevalence of HIV Infection in Childbearing Women in the United States.
Journal of the American Medical Association 1991;265:1704–8

1991

Edward A. Belongia, Craig W. Hedberg, Gerald J. Gleich, Karen E. White, Arthur N. Mayeno, David A. Loegering, Sandra L. Dunnette, Phyllis L. Pirie, Kristine L. MacDonald, Michael T. Osterholm
An Investigation of the Cause of the Eosinophilia–Myalgia Syndrome Associated with Tryptophan Use.
New England Journal of Medicine 1990;323:357–65

1990

Patricia M. Griffin, Robert V. Tauxe, Stephen C. Redd, Nancy D. Puhr, Nancy Hargrett–Bean, and Paul A. Blake
Emergence of Highly Trimethoprim–Sulfamethoxazole–Resistant
Shigella in a Native American Population: An Epidemiologic Study.

American Journal of Epidemiology1989;129:1042–50

1989

Chin–Yih Ou, Shirley Kwok, Sheila W. Mitchell, David H. Mack, John J. Sninsky, John W. Krebs, Paul Feorino, Donna Warfield, and Gerald Schochetman
DNA Amplification for Direct Detection of HIV–1 in DNA of Peripheral Blood Mononuclear Cells.
Science 1988;239:295–7

1988

Rebeca Rico-Hesse, Mark A. Pallansch, Baldev K. Nottay, Olen M. Kew
Geographic Distribution of Wild Poliovirus Type 1 Genotypes.
Virology 1987;160:311–22

1987

J. S. McDougal, M. S. Kennedy, J. M. Sligh, S. P. Cort, A. Mawle, J. K. A. Nicholson
Binding of HTLV–III/LAV to T4 + T Cells by a Complex of the 100K Viral Protein and the T4 Molecule
Science1986;231:382–5

1986

A L Reingold, A W Hightower, G A Bolan, E E Jones, H Tiendrebeogo, C V Broome, G W Ajello, C Adamsbaum, C Phillips, A Yada
Age–Specific Differences in Duration of Clinical Protection after Vaccination with Meningococcal Polsaccharide a Vaccine
The Lancet, 1985;2:114–8