Table 1. Recommended Adult Immunization Schedule for ages 19 years or older, United States, 2021

¶ = Recommended vaccination for adults who meet age requirement, lack documentation of vaccination, or lack evidence of past infection
§ = Recommended vaccination for adults with an additional risk factor or another indication
± = Recommended vaccination based on shared clinical decision-making
⇒ = No recommendation/Not applicable

adult vaccine schedule
Vaccine	19-26 years		27-49 years				50-64 years	≥65 years
Influenza inactivated (IIV) or Influenza recombinant (RIV4)	¶		1 dose annually¶				¶	¶
Influenza live attenuated (LAIV4)	¶		1 dose annually¶				⇒	⇒
Tetanus, diphtheria, pertussis (Tdap or Td)	1 dose Tdap each pregnancy; 1 dose Td/Tdap for wound management (see notes)§
Tetanus, diphtheria, pertussis (Tdap or Td)	1 dose Tdap, then Td or Tdap booster every 10 years¶
Measles, mumps, rubella (MMR)	1 or 2 doses depending on indication (if born in 1957 or later)¶							⇒
Varicella (VAR)	2 doses (if born in 1980 or later)¶			¶	§	2 doses§
Zoster recombinant (RZV)	⇒		⇒				2 doses¶
Human papillomavirus (HPV)	2 or 3 doses depending on age at initial vaccination or condition¶		27 through 45 years±		±	⇒	⇒	⇒
Pneumococcal conjugate (PCV13)	1 dose§							§
Pneumococcal conjugate (PCV13)	1 dose§							1 dose±
Pneumococcal polysaccharide (PPSV23)	1 or 2 doses depending on indication§							1 dose¶
Hepatitis A (HepA)	2 or 3 doses depending on vaccine§
Hepatitis B (HepB)	2 or 3 doses depending on vaccine§
Meningococcal A, C, W, Y (MenACWY)	1 or 2 doses depending on indication, see notes for booster recommendations§
Meningococcal B (MenB)	§	2 or 3 doses depending on vaccine and indication, see notes for booster recommendations§
Meningococcal B (MenB)	19 through 23 years±	§	§
Haemophilus influenzae type b (Hib)	1 or 3 doses depending on indication§

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