Important update: Healthcare facilities
CDC has updated select ways to operate healthcare systems effectively in response to COVID-19 vaccination. Learn more
Given new evidence on the B.1.617.2 (Delta) variant, CDC has updated the guidance for fully vaccinated people. CDC recommends universal indoor masking for all teachers, staff, students, and visitors to K-12 schools, regardless of vaccination status. Children should return to full-time in-person learning in the fall with layered prevention strategies in place.
The White House announced that vaccines will be required for international travelers coming into the United States, with an effective date of November 8, 2021. For purposes of entry into the United States, vaccines accepted will include FDA approved or authorized and WHO Emergency Use Listing vaccines. More information is available here.
Travel requirements to enter the United States are changing, starting November 8, 2021. More information is available here.

COVID-19 Vaccine Safety in Children and Teens

COVID-19 Vaccine Safety in Children and Teens
Updated July 20, 2022

What You Need to Know

  • CDC recommends COVID-19 vaccines for everyone ages 6 months and older, and COVID-19 boosters for everyone ages 5 years and older, if eligible.
  • Through continued safety monitoring, COVID-19 vaccination has been found to be safe for children and teens.
  • Millions of children and teens ages 5 through 17 years have already received at least one dose of a COVID-19 vaccine.
  • The known risks and possible severe complications of COVID-19 outweigh the potential risks of having a rare, adverse reaction to vaccination.
  • Use CDC’s COVID-19 booster tool to learn if and when your child or teen can get boosters to stay up to date with their COVID-19 vaccines.

Clinical Trials and Ongoing Safety Monitoring Show That COVID-19 Vaccination Is Safe for Children and Teens

Before authorizing or approving COVID-19 vaccines, scientists conducted clinical trials with thousands of children and teens to establish their safety and effectiveness. Learn more about how COVID-19 vaccines were developed and approved.

COVID-19 vaccines are being monitored under the most comprehensive and intense vaccine safety monitoring program in U.S. history. CDC monitors all COVID-19 vaccines after they are authorized or approved for use. CDC and U.S. Food and Drug Administration (FDA) continue to monitor vaccines, keep people informed of findings, and use data to make COVID-19 vaccination recommendations.

Serious Health Events after COVID-19 Vaccination Are Rare

Serious reactions after COVID-19 vaccination in children and teens are rare. When they are reported, serious reactions most frequently occur within a few days after vaccination.

Rare cases of myocarditis (inflammation of the heart muscle) and pericarditis (inflammation of the outer lining of the heart) have been reported after children and teens ages 5 years and older got the Pfizer-BioNTech COVID-19 vaccine. New studies have shown the rare risk of myocarditis and pericarditis associated with mRNA COVID-19 vaccination (Pfizer-BioNTech and Moderna)—mostly among males between the ages of 12 and 39 years—may be further reduced with a longer time between the first and second dose.

Febrile seizures were rare in COVID-19 vaccine clinical trials for young children and occurred at similar rates for both Pfizer and Moderna COVID-19 vaccines. Learn more about febrile seizures and vaccines.

A severe allergic reaction, like anaphylaxis, may happen after any vaccination, including COVID-19 vaccination, but this is rare. If your child experiences a severe allergic reaction after getting a COVID-19 vaccine, vaccine providers can rapidly provide care and call for emergency medical services, if needed.

If your child gets a COVID-19 vaccine and you think they might be having a severe allergic reaction after leaving the vaccination provider site, seek immediate medical care by calling 911.

People Cannot Get COVID-19 from Any COVID-19 Vaccine

mRNA vaccines, such as the Pfizer-BioNTech and Moderna vaccines, do not use the live virus that causes COVID-19 and do not interact with DNA in any way. Instead, mRNA vaccines teach the body how to fight the virus that causes COVID-19. Then, the body gets rid of the mRNA within a few days after vaccination.

There Is No Evidence That COVID-19 Vaccination Causes Problems Becoming Pregnant

There is no evidence that vaccine ingredients, including mRNA, or antibodies made following COVID-19 vaccination would cause any problems with becoming pregnant now or in the future. Learn more about COVID-19 vaccines for people who would like to have a baby someday.

Research on COVID-19 Vaccine Safety in Children

For a complete list of research, visit Vaccine Safety Publications.