Weight Status

Body mass index (BMI) was calculated for all of the Registry participants and a corresponding weight status was assigned based on age and BMI¹.  Among the Registry participants with a valid weight and height reported (n= 3084, 97.5%), 2.4% were underweight, 45.6% were normal weight, 23.6% were overweight, and 26% were obese.  Among the Registry participants who were under 20 years of age and had a valid weight and height reported (n= 1592), 3.3% were underweight, 61.1% were normal weight, 15.6% were overweight, and 18.7% were obese.  Among the Registry participants who were 20 years of age or above and who had a valid weight and height reported (n=1492), 1.4% were underweight, 29.6% were normal weight, 31.9% were overweight, and 33.5% were obese (Table 3).

Among people with hemophilia, obesity has been shown to decrease the range of joint motion and to increase clotting factor concentrate usage². The rate of obesity among participants under 20 years of age was higher compared to counterparts in a national health study. Nearly 19% of the Registry participants under 20 years of age were obese compared to 16.9% of the participants under 20 years of age examined in the National Health and Nutrition Examination Survey (2009-2010). The Registry participants 20 years old and above had lower obesity rates than those in the national health study (33.5% versus 35.7%).

Table 3: Weight status of the Registry participants under 20 years of age and 20 years of age and over, 2014

* BMI-for-age percentiles of age groups 2 to <20 years old were calculated and categorized using the CDC-recommended SAS® software program for the 2000 CDC Growth Charts.  Weight-for-height percentiles of age <2 years old were calculated and categorized using the CDC-recommended SAS program for the WHO growth charts.

** BMIs for individuals in this age group were calculated and categorized using CDC-recommended SAS® software program.

References

1. https://www.cdc.gov/healthyweight/assessing/bmi/adult_bmi/index.html; https://www.cdc.gov/healthyweight/assessing/bmi/childrens_bmi/about_childrens_bmi.html
2. Wong TE, Majumdar S, Adams E, Bergman S, Damiano ML, Deutsche J, Recht M; Healthy Weight Working Group. Overweight and obesity in hemophilia: a systematic review of the literature. Am J Prev Med. 2011 Dec;41(6 Suppl 4):S369-75.